The rule: 1) defines a drug screen, drug test, confirmation test, and participants; 2) requires all agencies receiving public funds to provide substance use treatment, to have written policies and procedures on drug testing, and a requirement to allow review of those policies and procedures by the Division; 3) requires agencies to notify participants of: the purpose of a drug screen, who will have access to results, the potential consequence of testing positive, and their right to request confirmation testing; 4) requires testing methodologies to meet the scientific standards developed by the Substance Abuse and Mental Health Services Administration; 5) establishes testing frequencies; 6) sets cut-off levels; 7) prescribes requirements for positive results; 8) prescribes sanctions; 9) requires agencies to not bill for confirmation tests that are returned as negative; 10) recommends that duplicate drug testing among the Department of Human Services' divisions should be avoided; 11) recommends addition methods to fully monitor treatment compliance; and 12) recommends the use of Medication Assisted Treatment.